Lisa Landgraf
Semmelweisstr. 14
04103 Leipzig

Tel: +49(0)341/97-12002
Fax: +49(0)341/97-12009
E-Mail: lisa.landgraf@medizin.uni-leipzig.de


Background and Position

Since January 2017 Lisa Landgraf is a Postdoc in the research group `Sono-Ray`at ICCAS. She received her diploma in Biology at the Friedrich-Schiller-University Jena in 2011, and finished her PhD degree at the Faculty of Medicine Jena in October 2015.

2011 – 2014
Lisa Landgraf was Ph.D. student at the Institute of Diagnostic and Interventional Radiology in Jena involved in a research project funded by the DFG ( Schwerpunktprogramm1313). Within this project she studied the effects of newly developed double sited gold at iron oxide nanoparticles on cell metabolism, DNA damage, ROS generation and internalization into endothelial cells to understand the processing of different nanoparticle types in vitro and possible clinical translation to the in vivo situation.

2010 – 2011
She was a young researcher at the Department of Genetics in Jena where she investigated virus induced gene silencing in Lepidium campestre and Araboidopsis.


Research Areas

  • cell biology
  • cancer treatment
  • focused ultrasound and radiation therapy
  • MR-guided focused ultrasound
  • PET/MR imaging

Publications

2017
Landgraf L, Nordmeyer D, Schmiel P, Gao Q, Ritz S, Gebauer J, Graß S, Diabaté S, Treuel L, Graf C, Rühl E, Landfester K, Mailänder V, Weiss C, Zellner R, Hilger I. Validation of weak biological effects by round robin experiments: cytotoxicity/biocompatibility of SiO2 and polymer nanoparticles in HepG2 cells. nature SCIENTIFIC REPORTS, revision submitted

2015
Landgraf L, Müller I, Ernst P, Schäfer M, Rosman C, Schick I, Köhler O, Oehring H, Breus V, Basché T, Sönnichsen C, Tremel W, Hilger I. Comparative evaluation of the impact on endothelial cells induced by different nanoparticle structures and functionalization. 2015, Beilstein Journal of Nanotechnology, 6: 300-312

Landgraf L, Christner C, Storck W, Schick I, Krumbein I, Dähring H, Haedicke K, Herrmann K-H, Teichgräber U, Reichenbach J, Tremel W, Tenzer S, Hilger I. A plasma protein corona enhances the biocompatibility of Au@Fe3O4 Janus particles. 2015, Biomaterials, 68: 77-88

2014
Landgraf L, Ernst P, Schick I, Köhler O, Oehring H, Tremel W, Hilger I. Antioxidative effects and harmlessness of asymmetric Au@Fe3O4 Janus particles on human blood cells. 2014, Biomaterials, 35(25): 6986–6997

Domey J, Haslauer L, Grau I, Strobel C, Kettering M, Hilger I. Probing the Cytotoxicity of Nanoparticles: Experimental Pitfalls and Artifacts. 2014, Book chapter in Bioanalytical Reviews, Series ISSN 1867-2086

ORAL PRESENTATIONS

Landgraf L, Ernst P, Schick I, Köhler O, Oehring H, Tremel W, Hilger I. Low cytotoxicity of asymmetric gold at iron oxide nanoparticles with suitable properties for multimodal imaging. European Molecular Imaging Meeting (EMIM) 2014, 04.-06.06.2014, Antwerpen, Belgien

Landgraf L, Ernst P, Schick I, Köhler O, Oehring H, Tremel W, Hilger I. Au@Fe3O4 Nanopartikel: Ein neuartiges Werkzeug in der Nanomedizin? 95. Deutscher Röntgenkongress 2014, 28.-31.05.2014, Hamburg, Deutschland

Landgraf L, Ernst P, Schick I, Köhler O, Oehring H, Tremel W, Hilger I. Au@Fe3O4 Janus particles as an innovative contrast agent for future multi-modal imaging. European Congress of Radiology (ECR) 2014, 06.-10.03.2014, Wien, Österreich

Haslauer L, Ernst P, Schick I, Köhler O, Tremel W, Hilger I. Inorganic Au@Fe3O4 and Au@MnO Janus particles: an innovative tool for future multi-modal imaging? Molekulare Bildgebung (MoBi) 2013, 28.-30.10.2013, Heidelberg, Deutschland

Haslauer L, Ernst P, Schick I, Köhler O, Tremel W, Hilger I. Interaktion von Januspartikeln mit Zellen des Blutgefäßsystems. 10. Tag der Nachwuchswissenschaftler, FZL Jena, 29.05.2013, Jena, Deutschland

POSTER

Landgraf L, Ernst P, Schick I, Köhler O, Oehring H, Tremel W, Hilger I. High biocompatibility of asymmetric gold at iron oxide nanoparticles with excellent properties as drug carriers and for multimodal imaging purposes. 10th International Conference on the Scientific and Clinical Applications of Magnetic Carriers, 10.-14.06.2014, Dresden, Deutschland