{"id":62277,"date":"2025-08-06T10:41:13","date_gmt":"2025-08-06T08:41:13","guid":{"rendered":"https:\/\/www.iccas.de\/?p=62277"},"modified":"2025-08-06T10:41:13","modified_gmt":"2025-08-06T08:41:13","slug":"new-method-helps-detect-brain-tumors-without-contrast-agents","status":"publish","type":"post","link":"https:\/\/www.iccas.de\/en\/new-method-helps-detect-brain-tumors-without-contrast-agents\/?&lang=en","title":{"rendered":"New method helps detect brain tumors without contrast agents"},"content":{"rendered":"<p>ICCAS employees <strong>Anne-Katrin Pfahl<\/strong> and <strong>Hannes K\u00f6hler<\/strong>, together with an interdisciplinary team, have published a new study <!--more-->on the more precise detection of brain tumor tissue during surgery. The results have been published in the current issue of the journal Neurosurgical Focus (Vol. 59, Issue 2, August 2025). Link: <a href=\"https:\/\/doi.org\/10.3171\/2025.5.FOCUS25333\">https:\/\/doi.org\/10.3171\/2025.5.FOCUS25333<\/a><\/p>\n<p>The aim of the study was to use <strong>hyperspectral imaging (HSI)<\/strong> in combination with special MRI data (known as FLAIR sequences) to visualize tissue changes that are difficult to detect using conventional methods \u2013 without the use of contrast agents. The hyperspectral camera provides a detailed \u201ccolor profile\u201d of the tissue, which allows conclusions to be drawn about the water content and thus possible tumor activity.<\/p>\n<p>As part of the study, tissue areas were analyzed with HSI during surgery in 15 patients. A specific measurement, known as the <strong>tissue water index (TWI)<\/strong>, proved to be a reliable indicator of abnormal FLAIR signals in MRI. These signals, in turn, indicate possible tumor areas that cannot be visualized in the image using contrast agents. The results show promising accuracy in distinguishing between healthy and altered tissue.<\/p>\n<p>The study impressively demonstrates how modern imaging technologies such as HSI can help to better detect brain tumors in the operating room\u2014for the benefit of patients and as a valuable decision-making aid for the surgical team. The close integration of medical technology research and clinical application is exemplary of the work carried out at ICCAS.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>ICCAS employees Anne-Katrin Pfahl and Hannes K\u00f6hler, together with an interdisciplinary team, have published a new study<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-62277","post","type-post","status-publish","format-standard","hentry","category-news"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>New method helps detect brain tumors without contrast agents - Innovation Center Computer Assisted Surgery<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/?&lang=en\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:locale:alternate\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New method helps detect brain tumors without contrast agents\" \/>\n<meta property=\"og:description\" content=\"ICCAS employees Anne-Katrin Pfahl and Hannes K\u00f6hler, together with an interdisciplinary team, have published a new study\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.iccas.de\/en\/new-method-helps-detect-brain-tumors-without-contrast-agents\/\" \/>\n<meta property=\"og:site_name\" content=\"Innovation Center Computer Assisted Surgery\" \/>\n<meta property=\"article:published_time\" content=\"2025-08-06T08:41:13+00:00\" \/>\n<meta name=\"author\" content=\"Administrator\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Administrator\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/\"},\"author\":{\"name\":\"Administrator\",\"@id\":\"https:\/\/www.iccas.de\/#\/schema\/person\/1fe9d5b749977ad026afde6eeb1bf5de\"},\"headline\":\"New method helps detect brain tumors without contrast agents\",\"datePublished\":\"2025-08-06T08:41:13+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/\"},\"wordCount\":496,\"commentCount\":0,\"articleSection\":[\"News\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/\",\"url\":\"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/\",\"name\":\"New method helps detect brain tumors without contrast agents\",\"isPartOf\":{\"@id\":\"https:\/\/www.iccas.de\/#website\"},\"datePublished\":\"2025-08-06T08:41:13+00:00\",\"author\":{\"@id\":\"https:\/\/www.iccas.de\/#\/schema\/person\/1fe9d5b749977ad026afde6eeb1bf5de\"},\"breadcrumb\":{\"@id\":\"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.iccas.de\/?&lang=en\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Neue Methode hilft bei der Erkennung von Hirntumoren ohne Kontrastmittel\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.iccas.de\/#website\",\"url\":\"https:\/\/www.iccas.de\/\",\"name\":\"Innovation Center Computer Assisted Surgery\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.iccas.de\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.iccas.de\/#\/schema\/person\/1fe9d5b749977ad026afde6eeb1bf5de\",\"name\":\"Administrator\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.iccas.de\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/4d7b579b767f3098d0ec012339493dee513fd6bd30b0c7d78ef003a5c993eccf?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/4d7b579b767f3098d0ec012339493dee513fd6bd30b0c7d78ef003a5c993eccf?s=96&d=mm&r=g\",\"caption\":\"Administrator\"},\"url\":\"https:\/\/www.iccas.de\/en\/author\/administrator\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"New method helps detect brain tumors without contrast agents - Innovation Center Computer Assisted Surgery","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/?&lang=en","og_locale":"en_US","og_type":"article","og_title":"[:en]New method helps detect brain tumors without contrast agents[:de]Neue Methode hilft bei der Erkennung von Hirntumoren ohne Kontrastmittel[:] - Innovation Center Computer Assisted Surgery","og_description":"ICCAS employees Anne-Katrin Pfahl and Hannes K\u00f6hler, together with an interdisciplinary team, have published a new study","og_url":"https:\/\/www.iccas.de\/en\/new-method-helps-detect-brain-tumors-without-contrast-agents\/","og_site_name":"Innovation Center Computer Assisted Surgery","article_published_time":"2025-08-06T08:41:13+00:00","author":"Administrator","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Administrator","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/#article","isPartOf":{"@id":"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/"},"author":{"name":"Administrator","@id":"https:\/\/www.iccas.de\/#\/schema\/person\/1fe9d5b749977ad026afde6eeb1bf5de"},"headline":"New method helps detect brain tumors without contrast agents","datePublished":"2025-08-06T08:41:13+00:00","mainEntityOfPage":{"@id":"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/"},"wordCount":496,"commentCount":0,"articleSection":["News"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/","url":"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/","name":"New method helps detect brain tumors without contrast agents","isPartOf":{"@id":"https:\/\/www.iccas.de\/#website"},"datePublished":"2025-08-06T08:41:13+00:00","author":{"@id":"https:\/\/www.iccas.de\/#\/schema\/person\/1fe9d5b749977ad026afde6eeb1bf5de"},"breadcrumb":{"@id":"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.iccas.de\/new-method-helps-detect-brain-tumors-without-contrast-agents\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.iccas.de\/?&lang=en"},{"@type":"ListItem","position":2,"name":"Neue Methode hilft bei der Erkennung von Hirntumoren ohne Kontrastmittel"}]},{"@type":"WebSite","@id":"https:\/\/www.iccas.de\/#website","url":"https:\/\/www.iccas.de\/","name":"Innovation Center Computer Assisted Surgery","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.iccas.de\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.iccas.de\/#\/schema\/person\/1fe9d5b749977ad026afde6eeb1bf5de","name":"Administrator","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.iccas.de\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/4d7b579b767f3098d0ec012339493dee513fd6bd30b0c7d78ef003a5c993eccf?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/4d7b579b767f3098d0ec012339493dee513fd6bd30b0c7d78ef003a5c993eccf?s=96&d=mm&r=g","caption":"Administrator"},"url":"https:\/\/www.iccas.de\/en\/author\/administrator\/"}]}},"_links":{"self":[{"href":"https:\/\/www.iccas.de\/en\/wp-json\/wp\/v2\/posts\/62277","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iccas.de\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iccas.de\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iccas.de\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iccas.de\/en\/wp-json\/wp\/v2\/comments?post=62277"}],"version-history":[{"count":4,"href":"https:\/\/www.iccas.de\/en\/wp-json\/wp\/v2\/posts\/62277\/revisions"}],"predecessor-version":[{"id":62281,"href":"https:\/\/www.iccas.de\/en\/wp-json\/wp\/v2\/posts\/62277\/revisions\/62281"}],"wp:attachment":[{"href":"https:\/\/www.iccas.de\/en\/wp-json\/wp\/v2\/media?parent=62277"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iccas.de\/en\/wp-json\/wp\/v2\/categories?post=62277"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iccas.de\/en\/wp-json\/wp\/v2\/tags?post=62277"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}