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ISO - Certivication

10.06.2020

headline-marker ProDial

Hemodialysis treatment affects only 0.1% of the total population. However, this complex, long-term and chronic procedure requires 5 to 10% of the total health care costs in industrialized countries. Although the treatment ensures life-sustaining detoxification, it does not prevent the 5 to 10 times higher mortality of those affected patients with end-stage renal disease compared to the general population.

Nowadays, quality and process control of hemodialysis treatment is based on a general evaluation of biochemical and procedural measures, which does not really influence the individual patient’s outcome in terms of mortality and dialysis tolerance. For this reason, the ProDial project aims to develop an individual analysis of the dialysis treatment and a personalized data generation and handling scheme. For this purpose, time-synchronous data of different dialysis aspects will be collected and evaluated. This includes patient and therapy characteristics, biomedical real-time feedback, process information and patient reported outcomes. Innovative and anonymized data collection methods, including the integration of portable personal devices and sensors, will ensure integrated, searchable and personalized data storage.

Novel mechanisms for finding significant correlations between the referenced data categories should enable the development of personalized real-time dialysis treatment procedures in the long term. These data-based algorithms can then be integrated into modern and intelligent dialysis centers and, thus, facilitate a truly personalized real-time treatment. Such a treatment would respond immediately to the individual co-morbidity and tolerability behavior of the patient.

Link to project page

05.06.2020

headline-marker AIQNET

Due to the new Medical Device Regulation of the EU, the requirements for reliable medical device data are continuously increasing. To prove their continuous safety and performance, a market observation of the products based on clinical studies is explicitly required, which also enables a comparative quality and performance evaluation. The market monitoring is expected to optimize the performance data of medical devices, but also to improve diagnosis and medical treatment. The acquisition, storage, and analysis of clinical data in compliance with the data protection regulations are essential for this evaluation. Currently, the market surveillance is often characterized by a lack of skilled personnel in industry and hospitals, cost pressure, legal uncertainty and IT systems with low interoperability.

These aspects will be addressed in the AIQNET project (Artificial Intelligence for Clinical Studies). With the help of artificial intelligence epidemiological, clinical, para-clinical and radiological data can be automatically analyzed and used for the performance evaluation of medical devices.

Therefore, a digital ecosystem that ensures compliance with legal and ethical frameworks through state-of-the-art architecture and security technologies will be conceptualized and developed in the project. Within the framework of the platform, a database will be created, which enables both the clinics and medical device manufacturers to use clinical data for research and development effectively and in compliance with the EU regulatory framework.

As part of the sub-project, ICCAS will develop a “Digital Patient Model” that integrates different perspectives on treatment and the patient. The aim is to improve AI-supported clinical quality and performance assessment based on previous knowledge about the patient and the treatment. This includes aspects of diagnosis and the disease, information on therapies and the specific characteristics of the patient.

Main project website

13.05.2019

headline-marker LYSiS

The aim is to develop a new laparoscopic imaging system and supporting non-invasive intraoperative measures to increase the identification and classification of risk structures and lesions for visceral, transplantation, thoracic and vascular surgery based on the latest high-resolution HSI technology. (read more)

03.07.2020

headline-marker SORLIC

Tumor diseases, traumatic damage and malformations often cause defects of body integrity, which makes plastic-reconstructive surgery necessary. Extensive defects require, among other things, the transfer of distant free flaps. Until now, the different pre- and intraoperative images have been analyzed and interpreted visually by the surgeon. However, there is no assistance system on the market that supports the intraoperative planning of reconstructive surgeries.
The SORLIC project aims at the development of such a mobile system, which will consist of a mobile cart, a measurement system, image processing functionalities for the automatic interpretation of image data, and a user interface for controlling the system and for generating medical documentation. It shall automatically recognize the perforator vessels and the supplied regions by means of imaging and propose a donor flap placement. This information will be projected onto the patient to support the surgeon in the decision making process.

05.06.2020

headline-marker MSI Endoscope

Aim of this project is to develop a real time pulse oximetry system based on endoscopic multispectral imaging. Relevant medical applications will be determined and preclinically evaluated.

headline-marker HSI – Laparo/Endoscopy

The project aims to acquire and analyse hyperspectral data with a laparoscopic HSI-system in the clinical context. Furthermore, methods for the automated classification and visualisation of tissue with hyperspectral data will be developed and implemented.

22.04.2018

headline-marker MR-Biopsy

The goal of the joint project ‘MR-Biopsy’ is to research a worldwide first MR safe flexible biopsy forceps. This should improve the minimally invasive and image-guided removal of tissue samples without the previous high X-ray and contrast agent exposure. (read more)

21.06.2017

headline-marker IMPACT

The goal of this project is the development of a mobile system for lung function diagnostics in emergency situations. Based on electrical impedance tomography (EIT), changes of electrical properties in the lung are measured using an easily applicable electrode belt. This allows for a three-dimensional imaging and functional analysis to assess ventilation status. (read more)

23.04.2018

headline-marker SONO-RAY

Das Projekt SONORAY hat zum Ziel, therapeutischen fokussierten Ultraschall (FUS) und Strahlentherapie (RT) zur Behandlung von malignen Tumoren sowie Tumormetastasen zu kombinieren. Die zugrunde liegende Hypothese ist, dass zwei Gewebe zerstörende Methoden/ Energien (Energie von hochintensiven akustischen Wellen und ionisierender Strahlung) effektiver im Kampf gegen Krebs sind, als wenn jeweils nur eine der beiden Energien angewendet wird. (read more)

13.05.2019

headline-marker CURE-OP

The aim of CURE-OP is to develop the first commercially available high intensity focused ultrasound (HIFU) platform specifically designed for combinational cancer therapy. Today, the most common treatment options to cure cancer are surgery, radiation therapy (RT), chemotherapy and targeted therapy including immunotherapy. The approach followed in the CURE-OP project is not to replace any of those options, but to use focused ultrasound to enhance their effectiveness, in this case, the outcome of radiotherapy. (read more)